陳凱園課題組

Chen Kaiyuan Lab

[email protected]

課題組長(zhǎng)

陳凱園,，所聘副研究員（Pre-PI）,，碩士生導(dǎo)師,。2021年博士畢業(yè)于華中農(nóng)業(yè)大學(xué)。主要從事植物CRISPR基因組編輯技術(shù)的開發(fā)以及在分子育種中的應(yīng)用,。以第一作者或共同一作在Molecular Plant期刊發(fā)表論文2篇，獲國(guó)家發(fā)明專利2項(xiàng)。

工作經(jīng)歷

2022/06 – 至今 中國(guó)農(nóng)業(yè)科學(xué)院農(nóng)業(yè)基因組研究所  副研究員

2022/06 – 至今 中國(guó)農(nóng)業(yè)科學(xué)院農(nóng)業(yè)基因組研究所  博士后

教育經(jīng)歷

2013/09 – 2021/06 華中農(nóng)業(yè)大學(xué)  植物病理學(xué) 博士

2009/09 – 2013/06 華中農(nóng)業(yè)大學(xué)楚天學(xué)院    生物工程 學(xué)士

研究方向

(1) 圍繞“優(yōu)薯計(jì)劃”,，利用基因組編輯技術(shù)創(chuàng)制馬鈴薯雄性不育系,，助力二倍體馬鈴薯雜交育種。

(2) 結(jié)合基因組編輯技術(shù),，探索可固定雜種優(yōu)勢(shì)的育種策略,。

(3) 在植物中開發(fā)并優(yōu)化基于CRISPR系統(tǒng)的遺傳操作技術(shù)。

Chen Kaiyuan, Pre-PI, Master Advisor, received the Ph.D. degree from Huazhong Agricultural University in 2021. His research focuses on the improvement of plant CRISPR genome editing technologies and their applications in molecular breeding. He has published two papers in Molecular Plant as the first author or co-first author, and obtained two invention patents.

Working Experience

2022/06 – Present  Agricultural Genomics Institute at Shenzhen - CAAS    Pre-PI

2022/06 – Present  Agricultural Genomics Institute at Shenzhen - CAAS    Postdoctoral Fellow

Education

2013/09 – 2021/06  Huazhong Agricultural University                   Plant Pathology    Ph.D.

2009/09 – 2013/06  Huazhong Agricultural University Chutian College   Bioengineering    Bachelor

Research Interest

(1) Creating genic male-sterility potatoes for diploid potato hybrid breeding by CRISPR technologies.

(2) Exploring breeding strategies for fixing heterosis by genome editing technologies.

(3) Developing and optimizing CRISPR-based technologies for the manipulation of plant genomes.

Selected Publication

1. Kaiyuan Chen, Runnan Ke, Manman Du, Yuqing Yi, Yache Chen, Xiaochun Wang, Lu Yao, Xin Hou, Lizhong Xiong, Yinong Yang, and Kabin Xie. A FLASH pipeline for arrayed CRISPR library construction and function discovery of Receptor-Like-Kinases in rice. Molecular Plant, 2022, 15(2):243-257  

2. Dan Ding#, Kaiyuan Chen#, Yuedan Chen, Hong Li, and Kabin Xie. Engineering Introns to Express RNA Guides for Cas9- and Cpf1-Mediated Multiplex Genome Editing. Molecular Plant, 2018, 11(4):542-552 （#Equal contributions; Best of Molecular Plant 2018）

3. Kaiyuan Chen, Hao Liu, Muhammad Tahir ul Qamar, Kabin Xie, Ling-Ling Chen. Advances in guide RNA design for editing plant genomes using CRISPR-Cas systems. In: Willmann, M. R. (ed.), Genome editing for precision crop breeding, Burleigh Dodds Science Publishing, Cambridge, UK, 2021. (Book Chapter )  

Patent

1. 謝卡斌,，陳凱園,，丁丹.  一種基于CRISPR系統(tǒng)的基因組編輯方法及其應(yīng)用.  專利號(hào)：ZL201711194336.6

2. 謝卡斌，陳凱園.  一種高通量的基因編輯方法.  專利號(hào)：ZL202010772166.0