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劉永鑫課題組

劉永鑫194-210.jpg

姓名:

劉永鑫

職稱(chēng):

研究員,,博士生導(dǎo)師

電話(huà)/傳真:

13810163414

電子郵件:

[email protected]

實(shí)驗(yàn)室主頁(yè):

https://www.x-mol.com/groups/liuyongxin

研究方向:

以宏基因組方法開(kāi)發(fā)為立足點(diǎn),解析人體基因組,、菌群與食品營(yíng)養(yǎng)三者的互作關(guān)系,,為綜合利用功能食品和腸道菌群提升人類(lèi)健康而努力。


 簡(jiǎn)歷介紹:


劉永鑫,,研究員,,博士生導(dǎo)師。

劉永鑫,,研究員,,博士生導(dǎo)師。2014年博士畢業(yè)于中國(guó)科學(xué)院大學(xué)生物信息學(xué)專(zhuān)業(yè),,之后在中國(guó)科學(xué)院遺傳與發(fā)育生物學(xué)研究所工作歷任博士后,、工程師、高級(jí)工程師,,2022年10月加入中國(guó)農(nóng)業(yè)科學(xué)院深圳農(nóng)業(yè)基因組研究所擔(dān)任課題組長(zhǎng),。研究方向?yàn)楹昊蚪M方法開(kāi)發(fā)、功能挖掘和科學(xué)傳播,。參與QIIME 2項(xiàng)目,,主導(dǎo)開(kāi)發(fā)了易擴(kuò)增子(EasyAmplicon)、易宏基因組(EasyMetagenome),、培養(yǎng)組(Culturome)分析流程,、數(shù)據(jù)分析網(wǎng)站(EVennImageGP) 和R包(amplicon,、ggClusterNet)等,,目標(biāo)是全面打造宏基因組領(lǐng)域方法學(xué)基礎(chǔ)設(shè)施,推動(dòng)微生物組學(xué)發(fā)展,。以(共同)第一或通訊作者在Nature Biotechnology,、Nature MicrobiologyiMeta等期刊發(fā)表論文20余篇,。合作在Science,、Cell Host & Microbe,、Microbiome等期刊發(fā)表論文20余篇,累計(jì)發(fā)表論文50余篇,,被引用13000+次,。主編《微生物組實(shí)驗(yàn)手冊(cè)》專(zhuān)著,由300多位同行參與,,共同打造本領(lǐng)域長(zhǎng)期更新的中文百科全書(shū),。創(chuàng)辦宏基因組公眾號(hào),15萬(wàn)+同行關(guān)注,,分享原創(chuàng)文章3千余篇,,累計(jì)閱讀量超4千萬(wàn),打造本領(lǐng)域最具影響力的科學(xué)傳播平臺(tái),。發(fā)起《iMeta》期刊,,聯(lián)合全球千位專(zhuān)家共同打造宏基因組學(xué)、微生物組和生物信息學(xué)頂刊,,解決我國(guó)本領(lǐng)域期刊出版卡脖子問(wèn)題,。


 個(gè)人經(jīng)歷:


工作經(jīng)歷:

2022/10 - 至今     中國(guó)農(nóng)業(yè)科學(xué)院深圳農(nóng)業(yè)基因組研究所 研究員

2021/1 – 2022/9    中國(guó)科學(xué)院遺傳與發(fā)育生物學(xué)研究所 高級(jí)工程師

2016/8 – 2020/12  中國(guó)科學(xué)院遺傳與發(fā)育生物學(xué)研究所 工程師

2014/7 – 2016/7    中國(guó)科學(xué)院遺傳與發(fā)育生物學(xué)研究所 博士后


教育經(jīng)歷:

2011/9 – 2014/6     中國(guó)科學(xué)院大學(xué) 博士研究生

2008/9 – 2011/6     東北農(nóng)業(yè)大學(xué) 碩士研究生

2004/9 – 2008/6     東北農(nóng)業(yè)大學(xué) 本科

個(gè)人經(jīng)歷

 團(tuán)體研究方向:


團(tuán)隊(duì)成員:

李亞慧 助理研究員;高云云 博士后,;侯輝宇 博士后,;Salsabeel Yousuf 博士后;白德鳳 博士后,;楊軍波 博士后,;宋露洋 副教授(訪(fǎng)問(wèn)學(xué)者);彭凱 博士,;許姍姍 博士,;羅豪 科研助理;馬闖 碩士,;楊海飛 碩士,;王惠玲 本科(實(shí)習(xí))

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研究?jī)?nèi)容:

實(shí)驗(yàn)室將以宏基因組方法開(kāi)發(fā)(圖1)為立足點(diǎn),重點(diǎn)關(guān)注三代測(cè)序和微生物單細(xì)胞等新技術(shù),,解析人體基因組,、菌群與食品營(yíng)養(yǎng)三者的互作關(guān)系(圖2),為綜合利用功能食品和腸道菌群提升人類(lèi)健康而努力,,并打造中國(guó)特色的科學(xué)傳播體系(圖3),。



20221107-203215.jpg

1. 宏基因組研究方法開(kāi)發(fā)(A) 宏基因組分析流程開(kāi)發(fā)和優(yōu)化:宏基因組領(lǐng)域現(xiàn)有的方法仍然處于初級(jí)階段,,需要不斷地進(jìn)行改進(jìn)和創(chuàng)新。擴(kuò)增子已經(jīng)有3套引用過(guò)萬(wàn)的成熟流程,,目前仍缺少標(biāo)準(zhǔn)化的宏基因組分析和可視化流程,,開(kāi)展相關(guān)工作有利于全面推動(dòng)本領(lǐng)域發(fā)展并爭(zhēng)奪國(guó)際制高點(diǎn),。(B) 去宿主實(shí)驗(yàn)和分析方法開(kāi)發(fā):動(dòng)植物和食品微生物組研究,都會(huì)受到大量宿主污染的困擾,,解決高宿主含量樣本微生物富集去宿主的卡脖子問(wèn)題,,將極大拓展宏基因組研究的應(yīng)用和發(fā)展。(C) 多組學(xué)整合分析方法開(kāi)發(fā):之前的研究以單一組學(xué)為主,,正在向多組學(xué)整合轉(zhuǎn)變,,開(kāi)發(fā)和優(yōu)化多組學(xué)整合分析方法將更好地還原微生物組的全貌,發(fā)現(xiàn)生物學(xué)規(guī)律的真相,,更準(zhǔn)確地回答科學(xué)問(wèn)題,。


20221107-203208.jpg


2. 人體基因組、菌群與食品營(yíng)養(yǎng)的關(guān)系,。(A) 菌群影響人類(lèi)健康的關(guān)鍵物種和基因:近年的研究表明腸道微生物組可能通過(guò)其代謝分子影響人類(lèi)健康,,解碼微生物基因組對(duì)揭示其潛在的功能非常重要。過(guò)去10年,,全球已發(fā)表上萬(wàn)個(gè)腸道宏基因組測(cè)序樣本,,以及挖掘的20余萬(wàn)個(gè)宏基因組組裝基因組(MAG),為一些功能菌的挖掘,、變化規(guī)律的驗(yàn)證提供了一定的數(shù)據(jù)基礎(chǔ),。但這些數(shù)據(jù)目前仍停留在數(shù)據(jù)階段,絕大多數(shù)的功能未知,,需要更系統(tǒng)的數(shù)據(jù)庫(kù)組織形式,、進(jìn)一步地挖掘和新方法的出現(xiàn)來(lái)解析其中的功能微生物和基因。(B) 食品營(yíng)養(yǎng)協(xié)同腸道菌群改善人類(lèi)健康:重點(diǎn)關(guān)注微生物對(duì)食品對(duì)人類(lèi)健康的改善,,以便更好理解微生物組在人類(lèi)營(yíng)養(yǎng)和健康中的作用,,并開(kāi)功能食品,從而推動(dòng)基于腸道菌群的精準(zhǔn)食品營(yíng)養(yǎng)學(xué)發(fā)展,,改善人類(lèi)健康,。


5c1252730cb5d04887fe34b93a3b6b4.png

圖3. 微生物組科學(xué)傳播體系構(gòu)建:綜述、專(zhuān)著和期刊

A. 綜述微生物組數(shù)據(jù)分析方法 (Protein Cell, 2021高被引,,2023),,助力同行快速理解并開(kāi)展分析。B. 綜述植物微生物組功能研究體系(Current Opinion in Microbiology, 2019),。C. 聯(lián)合同行編寫(xiě)《微生物組實(shí)驗(yàn)手冊(cè)》,,打造本領(lǐng)域持續(xù)更新的中文方法百科全書(shū)。D. 發(fā)起微生物組領(lǐng)域高起點(diǎn)新刊iMeta(目標(biāo)前10%,,IF > 15),,構(gòu)建全球華人主導(dǎo)的本領(lǐng)域國(guó)際話(huà)語(yǔ)權(quán)體系,解決本領(lǐng)域期刊出版的卡脖子問(wèn)題,。


研究進(jìn)展 

2023年主要進(jìn)展如下:正式發(fā)布了我國(guó)主導(dǎo)的擴(kuò)增子分析流程——易擴(kuò)增子EasyAmplicon(iMeta, 2023),,開(kāi)發(fā)了微生物組R語(yǔ)言分析最佳實(shí)踐(Protein & Cell, 2023),,評(píng)測(cè)了奇碳納米孔測(cè)序技術(shù)在宏基因組長(zhǎng)讀長(zhǎng)測(cè)序中的良好表現(xiàn)(Science of the Total Environment2023),,綜述了微生物組研究的過(guò)去,、現(xiàn)在和未來(lái)(Protein & Cell, 2023),此外易宏基因組EasyMetagenome分析流程,、網(wǎng)絡(luò)分析RggClusterNet持續(xù)更新中,,更新版預(yù)期于2024年初發(fā)布。


代表論著:


代表論文:

2023

1. Tao Wen#, Guoqing Niu#, Tong Chen, Qirong Shen, Jun Yuan*, Yong-Xin Liu*. 2023. The best practice for microbiome analysis using R. Protein & Cell pwad024. https://doi.org/10.1093/procel/pwad024 (IF = 21.1, Q1)

2. Kai Peng#, Yong-xin Liu#, Xinran Sun, Qiaojun Wang, Pengcheng Du, Yunzeng Zhang, Mianzhi Wang, Zhiqiang Wang, Ruichao Li*. 2023. Long-read metagenomic sequencing reveals that high-copy small plasmids shape the highly prevalent antibiotic resistance genes in animal fecal microbiome. Science of the Total Environment 164585. https://doi.org/10.1016/j.scitotenv.2023.164585 (IF = 9.8, Q1)

3. Yong-Xin Liu#*, Lei Chen#, Tengfei Ma#, Xiaofang Li, Maosheng Zheng, Xin Zhou, Liang Chen, Xubo Qian, Jiao Xi, Hongye Lu, Huiluo Cao, Xiaoya Ma, Bian Bian, Pengfan Zhang, Jiqiu Wu, Ren-You Gan, Baolei Jia, Linyang Sun, Zhicheng Ju, Yunyun Gao*, Tao Wen*, Tong Chen*. 2023. EasyAmplicon: An easy-to-use, open-source, reproducible, and community-based pipeline for amplicon data analysis in microbiome research. iMeta 2: e83. https://doi.org/10.1002/imt2.83 (新刊,,預(yù)計(jì)IF > 20, Q1)

4. Yunyun Gao, Danyi Li, Yong-Xin Liu*. 2023. Microbiome research outlook: past, present, and future. Protein & Cell pwad031. https://doi.org/10.1093/procel/pwad031 (IF = 21.1, Q1)

5. Yong-Xin Liu*, Chun-Lin Shi, Tengfei Ma, Wubin Ding, Danyi Li, Tong Chen*, Jingyuan Fu*, Shuang-Jiang Liu*. 2023. iMeta progress and acknowledgment of reviewers in 2022. iMeta 2: e89. https://doi.org/10.1002/imt2.89 (新刊,,預(yù)計(jì)IF > 20, Q1)

6. Wen Luo, Yuanli Li, Ruiping Luo, Gehong Wei, Yongxin Liu*, Weimin Chen*. 2023. Dodder Parasitism Leads to the Enrichment of Pathogen Alternaria and Flavonoid Metabolites in Soybean Root. Agronomy 13: 1571. https://doi.org/10.3390/agronomy13061571 (IF = 3.7, Q1)

7. Penghao Sun#, Mengli Wang#, Yong?Xin Liu, Luqi Li, Xuejun Chai, Wei Zheng, Shulin Chen1, Xiaoyan Zhu* and Shanting Zhao*. 2023.High-fat diet-disturbed gut microbiota-colonocyte interactions contribute to dysregulating peripheral tryptophan-kynurenine metabolism. Microbiome 11, 154, https://doi.org/10.1186/s40168-023-01606-x (IF = 15.5, Q1).

8. Yuanping Zhou#, Wenjiao Luo#, Maoxing Li, Qiong Wang, Yongxin Liu*, Huachun Guo*.2023. Summer Rice-Winter Potato Rotation Suppresses Various Soil-Borne Plant Fungal Pathogens. Agronomy 13, 2143 (IF = 3.7, Q1).


2022

1. Jiao Xi, Zanbo Ding, Tengqi Xu, Wenxing Qu, Yanzhi Xu, Yongqing Ma, Quanhong Xue, Yongxin Liu, Yanbing Lin. 2022. Maize Rotation Combined with Streptomyces rochei D74 to Eliminate Orobanche cumana Seed Bank in the Farmland. Agronomy 12: 3129. https://doi.org/10.3390/agronomy12123129 (IF = 3.949, Q1)


2021

1. Yong-Xin Liu#*, Yuan Qin#, Tong Chen#, Meiping Lu, Xubo Qian, Xiaoxuan Guo & Yang Bai*. (2021). A practical guide to amplicon and metagenomic analysis of microbiome data. Protein & Cell 12, 315-330, https://doi.org/10.1007/s13238-020-00724-8 (IF = 15.328, Highly Cited)

2. Yong-Xin Liu, Yuan Qin & Yang Bai*. (2019). Reductionist synthetic community approaches in root microbiome research. Current Opinion in Microbiology 49, 97-102, https://doi.org/10.1016/j.mib.2019.10.010 (IF = 7.584)

3. Wenjun Li#, Likun Wang#, Xiaofang Li*, Xin Zheng, Michael F. Cohen, Yong-Xin Liu*. 2022. Sequence-based Functional Metagenomics Reveals Novel Natural Diversity of Functioning CopA in Environmental Microbiomes. Genomics Proteomics Bioinformatics https://doi.org/10.1016/j.gpb.2022.08.006 (IF = 6.409)

4. Jingying Zhang#, Yong-Xin Liu#, Na Zhang#, Bin Hu#, Tao Jin#, Haoran Xu, Yuan Qin, Pengxu Yan, Xiaoning Zhang, Xiaoxuan Guo, Jing Hui, Shouyun Cao, Xin Wang, Chao Wang, Hui Wang, Baoyuan Qu, Guangyi Fan, Lixing Yuan, Ruben Garrido-Oter, Chengcai Chu* & Yang Bai*. (2019). NRT1.1B is associated with root microbiota composition and nitrogen use in field-grown rice. Nature Biotechnology 37, 676-684, https://doi.org/10.1038/s41587-019-0104-4 (IF = 68.164, Highly Cited, Hot Paper, Cover Story)

5. Sunde Xu#, Yong-Xin Liu#, Tomislav Cernava#, Hongkai Wang, Shugeng Cao, Yaqi Zhou, Gabriele Berg, Tie Xia, Xing-Xing Shen, Ziyue Wen, Chunshun Li, Baoyuan Qu, Hefei Ruan, Yunrong Chai, Xueping Zhou, Zhonghua Ma, Yan Shi, Yunlong Yu, Yang Bai*, Yun Chen*. (2022). Bacteria within the fungal fruiting-body microbiome reduce fungal infections in cereal by disrupting lipid rafts. Nature Microbiology 7, 831-843, https://doi.org/10.1038/s41564-022-01131-x (IF = 30.964)

6. Jingying Zhang#, Yong-Xin Liu#, Xiaoxuan Guo, Yuan Qin, Ruben Garrido-Oter*, Paul Schulze-Lefert*, Yang Bai*. (2021). High-throughput cultivation and identification of bacteria from the plant root microbiota. Nature Protocols 16, 988-1012, https://doi.org/10.1038/s41596-020-00444-7 (IF = 17.021, Highly Cited,)

7. Yong-Xin Liu, Meng Wang & Xiu-Jie Wang*. (2014). Endogenous small RNA clusters in plants. Genomics Proteomics Bioinformatics 12, 64-71, https://doi.org/10.1016/j.gpb.2014.04.003 (IF = 6.409)

8. Xu-Bo Qian#, Tong Chen#, Yi-Ping Xu, Lei Chen, Fu-Xiang Sun, Mei-Ping Lu* & Yong-Xin Liu. (2020). A guide to human microbiome research: study design, sample collection, and bioinformatics analysis. Chinese Medical Journal, https://doi.org/10.1097/cm9.0000000000000871 (IF = 6.151)

9. Jingying Zhang#, Na Zhang#, Yong-Xin Liu#, Xiaoning Zhang, Bin Hu, Yuan Qin, Haoran Xu, Hui Wang, Xiaoxuan Guo, Jingmei Qian, Wei Wang, Pengfan Zhang, Tao Jin*, Chengcai Chu* & Yang Bai*. (2018). Root microbiota shift in rice correlates with resident time in the field and developmental stage. Science China Life Sciences 61, 613-621, https://doi.org/10.1007/s11427-018-9284-4 (IF = 10.42, Cover Story)

10. Tong Chen, Haiyan Zhang, Yu Liu, Yong-Xin Liu*, Luqi Huang* (2021). EVenn: Easy to create repeatable and editable Venn diagrams and Venn networks online. Journal of Genetics and Genomics, https://doi.org/10.1016/j.jgg.2021.07.007 (IF = 5.733)

11. Tao Wen#, Penghao Xie#, Shengdie Yang, Guoqing Niu, Xiaoyu Liu, Zhexu Ding, Chao Xue, Yong-Xin Liu*, Qirong Shen, Jun Yuan*. (2022). ggClusterNet: An R package for microbiome network analysis and modularity-based multiple network layouts. iMeta 1: e32. https://doi.org/10.1002/imt2.32

12. Tong Chen, Yong-Xin Liu*, Luqi Huang*. (2022). ImageGP: An easy-to-use data visualization web server for scientific researchers. iMeta 1: e5. https://doi.org/10.1002/imt2.5

13. Yong-Xin Liu*, Tong Chen*, Danyi Li, Jingyuan Fu*, Shuang-Jiang Liu*. (2022). iMeta: Integrated meta-omics for biology and environments. iMeta 1: e15. https://doi.org/10.1002/imt2.15

14. Xubo Qian#, Yong-Xin Liu#, Xiaohong Ye, Wenjie Zheng, Shaoxia Lv, Miaojun Mo, Jinjing Lin, Wenqin Wang, Weihan Wang, Xianning Zhang & Meiping Lu*. (2020). Gut microbiota in children with juvenile idiopathic arthritis: characteristics, biomarker identification, and usefulness in clinical prediction. BMC Genomics 21, 286, https://doi.org/10.1186/s12864-020-6703-0 (IF = 4.560)

15. Yong-Xin Liu#, Wei Chang#, Ying-peng Han, Quan Zou, Mao-zu Guo & Wen-bin Li*. (2011). In silico detection of novel microRNAs genes in soybean genome. Agricultural Sciences in China 10, 1336-1345, https://doi.org/10.1016/S1671-2927(11)60126-0 (IF = 4.384)

16. Yong-Xin Liu, Ying-peng Han, Wei Chang, Quan Zou, Mao-zu Guo & Wen-bin Li*. (2010). Genomic analysis of microRNA promoters and their cis-acting elements in soybean. Agricultural Sciences in China 9, 1561-1570, https://doi.org/10.1016/S1671-2927(09)60252-2 (IF = 4.384)

17. Jing Li#, Yong-Xin Liu#, Ying-peng Han, Yong-guang Li, Mao-zu Guo, Wen-bin Li*. (2013). MicroRNA primary transcripts and promoter elements analysis in soybean (Glycine max L. Merril.). Journal of Integrative Agriculture 12, 1522-1529, https://doi.org/10.1016/S2095-3119(13)60500-6 (IF = 4.384)

18. 劉永鑫, 秦媛, 郭曉璇 & 白洋*. (2019). 微生物組數(shù)據(jù)分析方法與應(yīng)用. 遺傳 41, 845-826, https://doi.org/10.16288/j.yczz.19-222

19. Ancheng C. Huang#, Ting Jiang#, Yong-Xin Liu, Yue-Chen Bai, James Reed, Baoyuan Qu, Alain Goossens, Hans-Wilhelm Nützmann, Yang Bai* & Anne Osbourn*. (2019). A specialized metabolic network selectively modulates Arabidopsis root microbiota. Science 364, eaau6389, https://doi.org/10.1126/science.aau6389 (IF = 63.798, Highly Cited)

20. Evan Bolyen#, Jai Ram Rideout#, Matthew R. Dillon#, Nicholas A. Bokulich#, Christian C. Abnet, Gabriel A. Al-Ghalith, Harriet Alexander, Eric J. Alm, Manimozhiyan Arumugam, Francesco Asnicar, Yang Bai, Jordan E. Bisanz, Kyle Bittinger, Asker Brejnrod, Colin J. Brislawn, C. Titus Brown, Benjamin J. Callahan, Andrés Mauricio Caraballo-Rodríguez, John Chase, Emily K. Cope, Ricardo Da Silva, Christian Diener, Pieter C. Dorrestein, Gavin M. Douglas, Daniel M. Durall, Claire Duvallet, Christian F. Edwardson, Madeleine Ernst, Mehrbod Estaki, Jennifer Fouquier, Julia M. Gauglitz, Sean M. Gibbons, Deanna L. Gibson, Antonio Gonzalez, Kestrel Gorlick, Jiarong Guo, Benjamin Hillmann, Susan Holmes, Hannes Holste, Curtis Huttenhower, Gavin A. Huttley, Stefan Janssen, Alan K. Jarmusch, Lingjing Jiang, Benjamin D. Kaehler, Kyo Bin Kang, Christopher R. Keefe, Paul Keim, Scott T. Kelley, Dan Knights, Irina Koester, Tomasz Kosciolek, Jorden Kreps, Morgan G. I. Langille, Joslynn Lee, Ruth Ley, Yong-Xin Liu, Erikka Loftfield, Catherine Lozupone, Massoud Maher, Clarisse Marotz, Bryan D. Martin, Daniel McDonald, Lauren J. McIver, Alexey V. Melnik, Jessica L. Metcalf, Sydney C. Morgan, Jamie T. Morton, Ahmad Turan Naimey, Jose A. Navas-Molina, Louis Felix Nothias, Stephanie B. Orchanian, Talima Pearson, Samuel L. Peoples, Daniel Petras, Mary Lai Preuss, Elmar Pruesse, Lasse Buur Rasmussen, Adam Rivers, Michael S. Robeson, Patrick Rosenthal, Nicola Segata, Michael Shaffer, Arron Shiffer, Rashmi Sinha, Se Jin Song, John R. Spear, Austin D. Swafford, Luke R. Thompson, Pedro J. Torres, Pauline Trinh, Anupriya Tripathi, Peter J. Turnbaugh, Sabah Ul-Hasan, Justin J. J. van der Hooft, Fernando Vargas, Yoshiki Vázquez-Baeza, Emily Vogtmann, Max von Hippel, William Walters, Yunhu Wan, Mingxun Wang, Jonathan Warren, Kyle C. Weber, Charles H. D. Williamson, Amy D. Willis, Zhenjiang Zech Xu, Jesse R. Zaneveld, Yilong Zhang, Qiyun Zhu, Rob Knight & J. Gregory Caporaso*. (2019). Reproducible, interactive, scalable and extensible microbiome data science using QIIME 2. Nature Biotechnology 37, 852-857, https://doi.org/10.1038/s41587-019-0209-9 (IF = 68.164)

21. Wei Wang#, Jing Yang#, Jian Zhang, Yong-Xin Liu, Caiping Tian, Baoyuan Qu, Chulei Gao, Peiyong Xin, Shujing Cheng, Wenjing Zhang, Pei Miao, Lei Li, Xiaojuan Zhang, Jinfang Chu, Jianru Zuo, Jiayang Li, Yang Bai, Xiaoguang Lei* & Jian-Min Zhou*. (2020). An Arabidopsis secondary metabolite directly targets expression of the bacterial type III secretion system to inhibit bacterial virulence. Cell Host & Microbe 27, 601-613.e607, https://doi.org/10.1016/j.chom.2020.03.004 (IF = 31.316)

22. Leli Wang, Qihang Liu, Yuwei Chen, Xinlei Zheng, Chuni Wang, Yining Qi, Yachao Dong, Yue Xiao, Cang Chen, Taohong Chen, Qiuyun Huang, Zongzhao Zhai, Cimin Long, Huansheng Yang, Jianzhong Li, Lei Wang, Gaihua Zhang, Peng Liao, Yong-Xin Liu, Peng Huang, Jialu Huang, Qiye Wang, Huanhuan Chu, Jia Yin & Yulong Yin. (2022). Antioxidant potential of Pediococcus pentosaceus strains from the sow milk bacterial collection in weaned piglets. Microbiome 10: 83, https://doi.org/s40168-022-01278-z (IF = 16.837)

23. Wei Wang#, Bin Hu#, Dingyang Yuan, Yongqiang Liu, Ronghui Che, Yingchun Hu, Shujun Ou, Zhihua Zhang, Hongru Wang, Hua Li, Zhimin Jiang, Zhengli Zhang, Xiaokai Gao, Yahong Qiu, Xiangbing Meng, Yong-Xin Liu, Yang Bai, Yan Liang, Yi-Qin Wang, Lianhe Zhang, Legong Li, Sodmergen Sodmergen, Hai-Chun Jing, Jiayang Li & Chengcai Chu*. (2018). Expression of the nitrate transporter gene OsNRT1.1A/OsNPF6.3 confers high yield and early maturation in rice. The Plant Cell 30, 638-651, https://doi.org/10.1105/tpc.17.00809 (IF = 12.085, Highly Cited)

24. Maosheng Zheng, Nan Zhou, Shufeng Liu, Chenyuan Dang, Yong-Xin Liu, Shishi He, Yijun Zhao, Wen Liu & Xiangke Wang*. (2019). N2O and NO emission from a biological aerated filter treating coking wastewater: Main source and microbial community. Journal of Cleaner Production 213, 365-374, https://doi.org/10.1016/j.jclepro.2018.12.182 (IF = 11.072)

25. Qingwen Chen#, Ting Jiang#, Yong-Xin Liu, Haili Liu, Tao Zhao, Zhixi Liu, Xiaochao Gan, Asis Hallab, Xuemei Wang, Juan He, Yihua Ma, Fengxia Zhang, Tao Jin, M.Eric Schranz, Yong Wang, Yang Bai* & Guodong Wang*. (2019). Recently duplicated sesterterpene (C25) gene clusters in Arabidopsis thaliana modulate root microbiota. Science China Life Sciences 62, 947-958, https://doi.org/10.1007/s11427-019-9521-2 (IF = 10.42)

26. Handong Su#, Yalin Liu#, Yong‐Xin Liu, Zhenling Lv, Hongyao Li, Shaojun Xie, Zhi Gao, Junling Pang, Xiu‐Jie Wang, Jinsheng Lai & Fangpu Han*. (2016). Dynamic chromatin changes associated with de novo centromere formation in maize euchromatin. Plant Journal 1, 1-17, https://doi.org/10.1111/tpj.13305 (IF = 7.091)

27. Jiao Xi#, Beilei Lei#, Yong-Xin Liu, Zanbo Ding, Jiaxi Liu, Tengqi Xu, Lijun Hou, Siqi Han, Xun Qian, Yongqing Ma, Quanhong Xue, Jinming Gao, Jie Gu*, James M. Tiedje*, Yanbing Lin*. (2022). Microbial community roles and chemical mechanisms in the parasitic development of Orobanche cumana. iMeta 1: e31. https://doi.org/10.1002/imt2.31

28. Xin Zheng#, Likun Wang#, Linhao You, Yong-Xin Liu, Michael Cohen, Siyu Tian, Wenjun Li, Xiaofang Li. (2022). Dietary licorice enhances in vivo cadmium detoxification and modulates gut microbial metabolism in mice. iMeta 1: e7. https://doi.org/10.1002/imt2.7

29. Rong-Min Zhang, Jian Sun, Ruan-Yang Sun, Min-Ge Wang, Chao-Yue Cui, Liang-Xing Fang, Mei-Na Liao, Xiao-Qing Lu, Yong-Xin Liu, Xiao-Ping Liao, Ya-Hong Liu & Wei-Hua Chen. (2021). Source Tracking and Global Distribution of the Tigecycline Non-Susceptible tet(X). Microbiology Spectrum 9: e01164-01121. https://doi.org/10.1128/Spectrum.01164-21 (IF = 9.043)

30. Maosheng Zheng, Shishi He, Yueqi Feng, Mingyuan Wang, Yong-Xin Liu, Chenyuan Dang, Jiawen Wang*. (2021). Active ammonia-oxidizing bacteria and archaea in wastewater treatment systems. Journal of Environmental Sciences 102 273-282 https://doi.org/10.1016/j.jes.2020.09.039 (IF = 6.796)

31. Zhiyao Lv, Rui Dai, Haoran Xu, Yong‐Xin Liu, Bo Bai, Ying Meng, Haiyan Li, Xiaofeng Cao, Yang Bai, Xianwei Song, Jingying Zhang. (2021). The rice histone methylation regulates hub species of the root microbiota. Journal of Genetics and Genomics, https://doi.org/10.1016/j.jgg.2021.06.005  (IF = 5.733)

32. Jun Xu#, Jie-Ni Zhang#, Bo-Hui Sun, Qing Liu, Juan Ma, Qian Zhang, Yong-Xin Liu, Ning Chen* & Feng Chen*. (2021). The role of genotype and diet in shaping gut microbiome in a genetic Vitamin A deficient mouse model. Journal of Genetics and Genomics, https://doi.org/10.1016/j.jgg.2021.08.015 (IF = 5.733)


“#” represents the co-first author, “*” represents the corresponding author, IF is the abbreviation of impact factor of Journal Citation Reports.


劉永鑫課題組更新于2023年9月


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