梁翔禹課題組

	姓名：		梁翔禹
	職稱：		研究員,，博士生導(dǎo)師
	電話/傳真：		13162916069
	電子郵件：		[email protected]
	實(shí)驗(yàn)室主頁(yè)：		https://www.x-mol.com/groups/liangxiangyu
	研究方向：		基于自然生物的構(gòu)效關(guān)系，開(kāi)發(fā)高性能仿生結(jié)構(gòu)材料

簡(jiǎn)歷介紹：

梁翔禹,，研究員,，博士生導(dǎo)師

2019年博士畢業(yè)于復(fù)旦大學(xué)高分子科學(xué)系和聚合物分子工程國(guó)家重點(diǎn)實(shí)驗(yàn)室，先后在南方科技大學(xué)依次從事博士后和高級(jí)研究學(xué)者,。長(zhǎng)期專注于可降解生物材料,、仿生材料設(shè)計(jì)與制造、組織工程和軟材料極端力學(xué)等領(lǐng)域?，F(xiàn)主持廣東省自然科學(xué)基金（青年項(xiàng)目）和深圳市科技創(chuàng)新人才培養(yǎng)項(xiàng)目（博士啟動(dòng)）等,。近年來(lái)共發(fā)表20余篇論文和3項(xiàng)中國(guó)發(fā)明專利，主要發(fā)表在Nature communication,、Advanced materials,、Advanced Functional Materials、Small,、Biofabrication,、Materials Chemistry Frontiers、ACS Biomaterials Science & Engineering等國(guó)際權(quán)威期刊上,，其中以第一/通訊作者（含共同）在國(guó)際學(xué)術(shù)期刊上發(fā)表學(xué)術(shù)論文9篇?，F(xiàn)為廣東省自然科學(xué)基金項(xiàng)目入庫(kù)評(píng)審專家。

研究領(lǐng)域：

研究?jī)?nèi)容：

受大自然的啟發(fā),，人類已經(jīng)開(kāi)發(fā)了多種類型和多種功能的仿生材料（Bioinspired materials）,。特別是具有獨(dú)特且矛盾性質(zhì)的多層分級(jí)結(jié)構(gòu)的進(jìn)化發(fā)展，例如高強(qiáng)度和韌性組合的,，為現(xiàn)代先進(jìn)材料工程提供了巨大的靈感,。在合成復(fù)合材料中模仿自然的分級(jí)微觀結(jié)構(gòu)可以產(chǎn)生更耐損傷的結(jié)構(gòu)，并且一些生物靈感材料已經(jīng)在各種應(yīng)用中實(shí)現(xiàn),。我們的研究方向主要是基于自然生物的構(gòu)效關(guān)系,，開(kāi)發(fā)高性能仿生結(jié)構(gòu)材料及其先進(jìn)工藝技術(shù)，主要包括：第一,，可降解生物材料,；第二,，仿生材料結(jié)構(gòu)設(shè)計(jì)與制造；第三,，組織工程與藥物緩釋,。

研究進(jìn)展：

課題組以天然高分子和可降解合成高分子為主要研究材料，利用3D打印,、冷凍鑄造,、高分子成型與加工等方法，并結(jié)合計(jì)算機(jī)仿真等手段,，來(lái)研究仿生材料的結(jié)構(gòu)性能,，特別是生物材料的降解特性、力學(xué)性能以及極端場(chǎng)景下的應(yīng)用,。課題組的研究方向主要包括：第一，可降解生物材料的開(kāi)發(fā)與應(yīng)用,，如可降解塑料,、可降解醫(yī)用器械和可降解功能性器件等；第二,，通過(guò)仿生設(shè)計(jì)材料的微觀結(jié)構(gòu)和化學(xué)組分,，實(shí)現(xiàn)其在極端場(chǎng)景下的應(yīng)用，如柔性電子器件,、軟體機(jī)器人和防護(hù)器具等,；第三，通過(guò)對(duì)生物醫(yī)用材料的結(jié)構(gòu)形態(tài)和理化特性調(diào)控,，開(kāi)發(fā)出可軟硬組織修復(fù)與再生的多孔聚合物支架材料,。

代表論著：

代表論文：

(# Equal contribution; * Corresponding author)

1. Xiangyu Liang, Guangda Chen, Iek Man Lei, Pei Zhang, Zeyu Wang, Xingmei Chen, Mengze Lu, Jiajun Zhang, Zongbao Wang, Taolin Sun, Yang Lan and J. Liu*. Impact-Resistant Hydrogels by Harnessing 2D Hierarchical Structures. Advanced Materials, 2022, 2207587. (Cover paper)

2. Xiangyu Liang, Guangda Chen, Shaoting Lin, Jiajun Zhang, Liu Wang, Pei Zhang, Yang Lan, Ji Liu*. Bioinspired 2D Isotropically Fatigue-Resistant Hydrogels. Advanced Materials, 2022, 34, 2107106. (Cover paper).

3. Xiangyu Liang, Guangda Chen, Shaoting Lin, Jiajun Zhang, Liu Wang, Pei Zhang, Zeyu Wang, Zongbao Wang, Yang Lan, Qi Ge, Ji Liu*. Anisotropically Fatigue-Resistant Hydrogels. Advanced Materials, 2021, 33, 2102011.

4. Guangda Chen# , Xiangyu Liang#, Pei Zhang, Shaoting Lin, Ziyi Yu and Ji Liu?, Bioinspired 3D Printing of Functional Materials by Harnessing Enzyme-Induced Biomineralization. Advanced Functional Materials, 2022, 32, 2113262. (Co-first author, Cover paper)

5. Xiangyu Liang, Jingming Gao, Weike Xu, Xiuli Wang, Yang Shen, Jingyu Tang, Shuquan Cui, Xiaowei Yang, Qingsong Liu, Lin Yu, Jiandong Ding*. Structural Mechanics of 3D-printed Poly(lactic acid) Scaffolds with Tetragonal, Hexagonal and Wheel-like Designs. Biofabrication, 2019, 11, 035009.

6. Xiangyu Liang, Yongli Qi, Zhen Pan, Yao He, Xiangnan Liu, Shuquan Cui, Jiandong Ding*. Design and Preparation of Quasi-spherical Salt Particles as Water-soluble Porogens to Fabricate Hydrophobic Porous Scaffolds for Tissue Engineering and Tissue Regeneration. Materials Chemistry Frontiers, 2018, 2, 1539-1553.

7. Xiangyu Liang#, Pingguo Duan#, Jingming Gao, Runsheng Guo, Zehua Qu, Xiaofeng Li, Yao He, Haoqun Yao, Jiandong Ding*. Bilayered PLGA/PLGA-HAp Composite Scaffold for Osteochondral Tissue Engineering and Tissue Regeneration. ACS Biomaterials Science & Engineering, 2018, 4, 3506-3521.

8. Xiangyu Liang, Junjie Wen, Caihong Wen, Bo Wang, Jianyu Chen, Li Zhou*. Preparation of O-hydroxypropyl-N-butyl Chitosan under Microwave Irradiation. Journal of Applied Polymer Science. 2015, 132, 41527.

9. Yue Tao,# Xiangyu Liang,# Jun Zhang, Iek Man Lei, Ji Liu*. Polyurethane Vitrimers: Chemistry, Properties and Applications. Journal of Polymer Science, 2022, 1-21. DOI: 10.1002/pol.20220625. (Co-first author)

10. Pei Zhang, Iek Man Lei, Guangda Chen, Jingsen Lin, Xingmei Chen, Jiajun Zhang, Chengcheng Cai, Xiangyu Liang and J. Liu*. Integrated 3D Printing of Flexible Electroluminescent Devices and Soft Robots, Nature Communication, 2022, 13, 4775. (Cover paper)

11. Jiajun Zhang,# Lulu Wang,# Yu Xue,# Iek Man Lei, Xingmei Chen, Pei Zhang, Chengcheng Cai, Xiangyu Liang, Yi Lu, Ji Liu*.Engineering Electrodes with Robust Conducting Hydrogel Coating for Neural Recording and Modulation, Advanced Materials, 2022, 35(3), 202209324. (Cover paper)

12. Kuan Zhang,# Xingmei Chen,# Yu Xue,# Jingsen Lin, Xiangyu Liang, Jiajun Zhang, Jun Zhang, Guangda Chen, Chengcheng Cai, Ji Liu*. Tough Hydrogel Bioadhesives for Sutureless Wound Sealing, Hemostasis and Biointerfaces, Advanced Functional Materials, 2022, 32(15), 2111465.

13. Xingmei Chen, Jun Zhang, Guangda Chen, Yu Xue, JiaJun Zhang, Xiangyu Liang, Iek Man Lei, Jingsen Lin, Ben Xu, Ji Liu*. Hydrogel Bioadhesives with Extreme Acid-Tolerance for Gastric Perforation Repairing. Advanced Functional Materials, 2022, 32, 2202285. (Cover paper)

14. Jun Zhang,# Yaya Wang,# JiaJun Zhang, Iek Man Lei, Guangda Chen, Yu Xue, Xiangyu Liang, Daozeng Wang, Guigen Wang, Sisi He,* Ji Liu*. Robust Hydrogel Adhesion by Harnessing Bioinspired Interfacial Mineralization. Small, 2022, 18, 202201796.

15. Xiang Yao, Ruili Liu, Xiangyu Liang, Jiandong Ding*. Critical Areas of Proliferation of Single Cells on Micropatterned Surfaces and Corresponding Cell Type Dependence. ACS Applied Materials & Interfaces, 2019, 11(17): 15366-15380.

代表專利：

1. 丁建東，梁翔禹,，高鏡銘,，一種車輪狀多孔支架及其制備方法與應(yīng)用，中國(guó)發(fā)明專利,，2019,，NO：201910116354.5。（已授權(quán)）

2. 劉吉,，梁翔禹,，張加俊，陳廣大,，一種抗疲勞水凝膠的制備方法及其應(yīng)用,，中國(guó)發(fā)明專利，2021,，NO: 202110106029.8,。（已授權(quán)）

3. 劉吉,，陳廣大，梁翔禹,，一種礦化水凝膠的制備方法及其應(yīng)用,，中國(guó)發(fā)明專利，2021,，NO：202111047086.X,。（審查中）

梁翔禹課題組更新于2023年9月

上一篇：張江課題組
|
下一篇：常賀坦課題組

返回列表頁(yè)